[CAS NO. ] IFN-alpha 2/IFNA2 Protein, Human (P.pastoris)

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PRODUCTS SPECIFICATIONS

Catalog

HY-P73246

Brand

MCE

CAS

DESCRIPTION

Overview

MDL	-
Molecular Weight	Approximately 19.3 kDa
Molecular Formula	-
SMILES	-

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Summary

IFN-alpha 2 (IFNA2), belongs to type I interferon family, is a protein secreted by cells infected by a virus and acting on other cells to inhibit viral infection ^[1] . IFN-alpha 2 exerts cytotoxic activity against CD8 ⁺ T cells and induces CD4 ⁺ T cell depletion ^[3] . IFN-alpha 2/IFNA2 Protein, Human (P.pastoris) contains 165 a.a., is produced in yeast strain P. pastoris with tag free.

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Solution.

Source

P. pastoris

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References

[1] Abraham S, et al. Gene therapy with plasmids encoding IFN-β or IFN-α14 confers long-term resistance to HIV-1 in humanized mice. Oncotarget. 2016 Nov 29;7(48):78412-78420.
[2] Zhang SY, et al. Inborn errors of interferon (IFN)-mediated immunity in humans: insights into the respective roles of IFN-alpha/beta, IFN-gamma, and IFN-lambda in host defense. Immunol Rev. 2008 Dec;226:29-40.