[CAS NO. ] AMIGO2 Protein, Human (HEK293, His)

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PRODUCTS SPECIFICATIONS

Catalog

HY-P7495

Brand

MCE

CAS

DESCRIPTION

Overview

MDL	-
Molecular Weight	58-85 kDa
Molecular Formula	-
SMILES	-

For research use only. We do not sell to patients.

Summary

AMIGO2 Protein, Human (HEK293, His) is an 58-85 kDa AMIGO2 protein fused His-tag expressed in HEK 293 cells. AMIGO2 Protein, Human (HEK293, His) interacts with PDK1 to activate the Akt pathway localizated to the plasma membrane ^[1] .

Appearance

Lyophilized powder.

Source

HEK293

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Room temperature in continental US; may vary elsewhere.

References

[1] Hyojin Park, et al.AMIGO2, a novel membrane anchor of PDK1, controls cell survival and angiogenesis via Akt activation. J Cell Biol
[2] Zhilin Li, et al. AMIGO2 modulates T cell functions and its deficiency in mice ameliorates experimental autoimmune encephalomyelitis. Brain Behav Immun. 2017 May;62:110-123.