[CAS NO. ] Biglycan Protein, Human (HEK293, His)

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PRODUCTS SPECIFICATIONS

Catalog

HY-P7663

Brand

MCE

CAS

DESCRIPTION

Overview

MDL	-
Molecular Weight	40-90 kDa
Molecular Formula	-
SMILES	-

For research use only. We do not sell to patients.

Summary

Biglycan Protein, Human (HEK293, His) is a recombinant human Biglycan produced in HEK293 cells with a His tag. Biglycan, a small leucine-rich proteoglycan, acts as a danger signal and is classically thought to promote macrophage recruitment via Toll-like receptors (TLR) 2 and 4 ^[1] .

Appearance

Lyophilized powder.

Source

HEK293

Shipping

Room temperature in continental US; may vary elsewhere.

References

[1] Wang B, et al. Biglycan expression correlates with aggressiveness and poor prognosis of gastric cancer. Exp Biol Med (Maywood). 2011;236(11):1247-1253.
[2] Poluzzi C, et al. Biglycan evokes autophagy in macrophages via a novel CD44/Toll-like receptor 4 signaling axis in ischemia/reperfusion injury. Kidney Int. 2019;95(3):540-562.