Calumenin Protein, Human (HEK293, His)
PRODUCTS SPECIFICATIONS
DESCRIPTION
Overview
| MDL | - |
|---|---|
| Molecular Weight | 40-55 kDa |
| Molecular Formula | - |
| SMILES | - |
Summary
Calumenin Protein, Human (296a.a, HEK293, His), a recombinant human Calumenin produced in HEK293 cells, has a His tag at the N-terminus. Calumenin protein (CP) is located within the endoplasmic reticulum Ca 2+ binding proteins. Calumenin as a suppressor of cell migration and tumor metastasis. Calumenin binds to and stabilizes fibulin-1, leading to inactivation of extracellular signal-regulated kinases 1 and 2 (ERK1/2) signaling [1] [2] .
Appearance
Lyophilized powder.
Source
HEK293
Shipping
Room temperature in continental US; may vary elsewhere.
References
- [1] Yu Wang, et al. Calumenin relieves cardiac injury by inhibiting ERS-initiated apoptosis during viral myocarditis. Int J Clin Exp Pathol. 2017 Jul 1;10(7):7277-7284.
- [2] Pengli Zheng, et al. Calumenin and fibulin-1 on tumor metastasis: Implications for pharmacology. Pharmacol Res. 2015 Sep;99:11-5.