[CAS NO. 195822-23-2]  LQZ-7I

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PRODUCTS SPECIFICATIONS [195822-23-2]

Catalog
SLK-E0108
Brand
Selleck
CAS
195822-23-2

DESCRIPTION [195822-23-2]

Overview

MDLMFCD00607076
Molecular Weight348.35
Molecular FormulaC₂₀H₁₄F₂N₄
SMILESFC1=CC=C(NC2=NC3=CC=CC=C3N=C2NC4=CC=C(F)C=C4)C=C1

For research use only.

Storage

3 years,-20°C,powder
1 years,-80°C,in solvent

Shipping

Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)

Preparing Stock Solutions

1 mg5 mg10 mg
1 mM2.8707 mL14.3534 mL28.7068 mL
5 mM0.5741 mL2.8707 mL5.7414 mL
10 mM0.2871 mL1.4353 mL2.8707 mL
50 mM0.0574 mL0.2871 mL0.5741 mL

Description

LQZ-7I is a novel selectively inhibitor of with IC50s of 4.8 µM and 3.1 µM in prostate cancer cell lines PC-3 and C4-2, respectively. LQZ-7I orally effectively inhibits xenograft tumor growth and induces survivin loss in tumors.

Targets

survivin [1]
(in PC-3 Cells)
survivin [1]
(in C4-2 Cells)
4.8 µM(ic50)3.1 µM(ic50)