[CAS NO. 375835-43-1]  Necrostatin-34 (Nec-34)

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PRODUCTS SPECIFICATIONS [375835-43-1]

Catalog
SLK-E0301
Brand
Selleck
CAS
375835-43-1

DESCRIPTION [375835-43-1]

Overview

MDL-
Molecular Weight384.48
Molecular FormulaC18H16N4O2S2
SMILESO=C(NC1=NC=CS1)CSC2=C(C#N)C(C3=CC=C(C)C=C3)CC(N2)=O

For research use only.

Storage

3 years,-20°C,powder
1 years,-80°C,in solvent

Shipping

Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)

Preparing Stock Solutions

1 mg5 mg10 mg
1 mM2.6009 mL13.0046 mL26.0092 mL
5 mM0.5202 mL2.6009 mL5.2018 mL
10 mM0.2601 mL1.3005 mL2.6009 mL
50 mM0.0520 mL0.2601 mL0.5202 mL

Description

Necrostatin-34 (Nec-34) is a small molecule inhibitor of with an IC50 of 0.13 μM in L929 cells.

Targets

RIPK1 kinase [1]
(in L929 cell)
0.13 μM