[CAS NO. 864289-85-0]  C-021

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PRODUCTS SPECIFICATIONS [864289-85-0]

Catalog
SLK-E0486
Brand
Selleck
CAS
864289-85-0

DESCRIPTION [864289-85-0]

Overview

MDL-
Molecular Weight467.65
Molecular FormulaC27H41N5O2
SMILES-

For research use only.

Storage

3 years,-20°C,powder
1 years,-80°C,in solvent

Shipping

Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)

Preparing Stock Solutions

1 mg5 mg10 mg
1 mM2.1384 mL10.6918 mL21.3835 mL
5 mM0.4277 mL2.1384 mL4.2767 mL
10 mM0.2138 mL1.0692 mL2.1384 mL
50 mM0.0428 mL0.2138 mL0.4277 mL

Description

C-021 is a potent antagonist with IC50 values are 0.14 μM and 39 nM for inhibition of chemotaxis in human and mouse respectively.

Targets

CCR4 [1]
(in the [35S]GTPγS-binding and mouse chemotaxis assay)
CCR4 [1]
(in the [35S]GTPγS-binding and human chemotaxis assay)
39 nM0.14 μM