[CAS NO. 66-27-3] Methyl methanesulfonate
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PRODUCTS SPECIFICATIONS [66-27-3]
Catalog
SLK-E0609
Brand
Selleck
CAS
66-27-3
DESCRIPTION [66-27-3]
Overview
| MDL | MFCD00007557 |
|---|---|
| Molecular Weight | 110.13 |
| Molecular Formula | C2H6O3S |
| SMILES | S(OC)(C)(=O)=O |
For research use only.
Storage
2 years -20°C liquid
Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)
Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)
Shipping
Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)
Description
Methyl methanesulfonate (MMS), a , modifies both guanine (to 7-methylguanine) and adenine (to 3-methlyladenine) to cause base mispairing and replication blocks, respectively.
Targets
| DNA alkylator [1] |
In vitro
Methyl methanesulfonate(MMS) is used for DNA damaging agent to induce mutagenesis. The repair of MMS-induced heat-labile damage requires the base excision repair protein XRCC1, and is independent of Homologous recombination in both S.cerevisiae and mammalian cells.
References
Synonyms
Methanesulfonic acid, methyl ester
Methyl methanesulphonate
MMS
Methyl methanesulfonate
Methyl methylsulfonate
NSC 50256
Methyl mesylate
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