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Catalog:
SLK-E1059
Brand:
Selleck
CAS:
2561494-77-5
Overview
MDL
-
Molecular Weight
443.46
Molecular Formula
C24H21N5O4
SMILES
-
For research use only.
Storage
3 years,-20°C,powder 1 years,-80°C,in solvent
Shipping
Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)
Preparing Stock Solutions
1 mg
5 mg
10 mg
1 mM
2.2550 mL
11.2750 mL
22.5499 mL
5 mM
0.4510 mL
2.2550 mL
4.5100 mL
10 mM
0.2255 mL
1.1275 mL
2.2550 mL
50 mM
-
-
-
Description
UNC6934 is a a chemical probe targeting the . UNC6934 is a potent antagonist of with a Kd (SPR) of 80 nM and is selective for NSD2-PWWP1 over 14 other PWWP domains including NSD3-PWWP1 UNC6934 disrupts the NSD2-PWWP1 interaction with H3K36me2 nucleosomes in U2OS cells as measured by a NanoBret assay with an IC50 of 1.09 μM.