[CAS NO. 72873-74-6]  SKF-86002

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PRODUCTS SPECIFICATIONS [72873-74-6]

Distributor
Catalog
SLK-E2630
Brand
Selleck
CAS
72873-74-6

DESCRIPTION [72873-74-6]

Overview

MDLMFCD00869367
Molecular Weight297.35
Molecular FormulaC16H12FN3S
SMILESFC1=CC=C(C=C1)C1=C(N2CCSC2=N1)C1=CC=NC=C1

For research use only.

Storage

3 years,-20°C,powder
1 years,-80°C,in solvent

Shipping

Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)

Preparing Stock Solutions

1 mg5 mg10 mg
1 mM3.3630 mL16.8152 mL33.6304 mL
5 mM0.6726 mL3.3630 mL6.7261 mL
10 mM0.3363 mL1.6815 mL3.3630 mL
50 mM0.0673 mL0.3363 mL0.6726 mL

Description

SKF-86002 is an orally active inhibitor, inhibits lipopolysaccharide (LPS)-stimulate human monocyte production with IC50 of 1 μM, also inhibits lipoxygenase- and cyclooxygenase-mediated metabolism of .

Targets

p38 MAPK [1]TNF-α [1]IL-1 [1]
(in the cytokine synthesis inhibition bioassay and radiocompetitive binding assay)
1 μM