[CAS NO. 2172617-15-9]  YKL 06-061

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PRODUCTS SPECIFICATIONS [2172617-15-9]

Catalog
SLK-S0051
Brand
Selleck
CAS
2172617-15-9

DESCRIPTION [2172617-15-9]

Overview

MDLMFCD32173438
Molecular Weight527.66
Molecular FormulaC30H37N7O2
SMILESO=C1N(C2CCC2)C3=NC(NC4=CC=C(N5CCN(C)CC5)C=C4OC)=NC=C3CN1C6=C(C)C=CC=C6C

For research use only.

Storage

3 years,-20°C,powder
1 years,-80°C,in solvent

Shipping

Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)

Preparing Stock Solutions

1 mg5 mg10 mg
1 mM1.8952 mL9.4758 mL18.9516 mL
5 mM0.3790 mL1.8952 mL3.7903 mL
10 mM0.1895 mL0.9476 mL1.8952 mL
50 mM---

Description

YKL 06-061 is a potent and selective inhibitor with IC50 of 6.56 nM, 1.77 nM and 20.5 nM for SIK1, SIK2 and SIK3, respectively.

Targets

SIK2 [1]
(Cell-free assay)
SIK1 [1]
(Cell-free assay)
SIK3 [1]
(Cell-free assay)
1.77 nM6.56 nM20.5 nM