[CAS NO. 897732-93-3]  APD597

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PRODUCTS SPECIFICATIONS [897732-93-3]

Catalog
SLK-S0110
Brand
Selleck
CAS
897732-93-3

DESCRIPTION [897732-93-3]

Overview

MDL-
Molecular Weight479.55
Molecular FormulaC21H29N5O6S
SMILESO=C(OC(C)C)N(CC1)CCC1OC2=C(OC)C(NC3=CC=C(S(=O)(C)=O)N=C3C)=NC=N2

For research use only.

Storage

3 years,-20°C,powder
1 years,-80°C,in solvent

Shipping

Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)

Preparing Stock Solutions

1 mg5 mg10 mg
1 mM2.0853 mL10.4264 mL20.8529 mL
5 mM0.4171 mL2.0853 mL4.1706 mL
10 mM0.2085 mL1.0426 mL2.0853 mL
50 mM0.0417 mL0.2085 mL0.4171 mL

Description

APD-597 (JNJ-38431055) is a potent and selective agonist with EC50 of 46 nM for hGPR119 and an inhibitor of with IC50 of 5.8 μM. APD-597 (JNJ-38431055) is developed for treating Type 2 diabetes (T2D).

Targets

hGPR119 [1]
(Cell-free assay)
CYP2C9 [1]
(Cell-free assay)
46 nM(EC50)5.8 μM