[CAS NO. 2306178-56-1] DMX-5084
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PRODUCTS SPECIFICATIONS [2306178-56-1]
Store
Catalog
SLK-S0268
Brand
Selleck
CAS
2306178-56-1
DESCRIPTION [2306178-56-1]
Overview
| MDL | - |
|---|---|
| Molecular Weight | 361.39 |
| Molecular Formula | C21H19N3O3 |
| SMILES | O=C1C2=C(N(C3=CC=CC=C3)C=C2C4=CC=C(OCCOC)C=C4)N=CN1 |
For research use only.
Storage
3 years,-20°C,powder
1 years,-80°C,in solvent
1 years,-80°C,in solvent
Shipping
Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)
Preparing Stock Solutions
| 1 mg | 5 mg | 10 mg | |
| 1 mM | 2.7671 mL | 13.8355 mL | 27.6709 mL |
| 5 mM | 0.5534 mL | 2.7671 mL | 5.5342 mL |
| 10 mM | 0.2767 mL | 1.3835 mL | 2.7671 mL |
| 50 mM | 0.0553 mL | 0.2767 mL | 0.5534 mL |
Description
DMX-5804 is a potent, orally active and selective inhibitor of with IC50 of 3 nM for human MAP4K4. DMX-5804 is more potent on human MAP4K4 with pIC50 of 8.55 than MINK1/MAP4K6 and TNIK/MAP4K7 with pIC50 of 8.18 and 7.96, respectively.
Targets
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