[CAS NO. 1534358-79-6]  COH000

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PRODUCTS SPECIFICATIONS [1534358-79-6]

Store
Catalog
SLK-S0309
Brand
Selleck
CAS
1534358-79-6

DESCRIPTION [1534358-79-6]

Overview

MDL-
Molecular Weight419.47
Molecular FormulaC25H25NO5
SMILESO=C(C1=C(C(OC)=O)[C@]2([H])C=C[C@@]1([C@H](NC3=CC=CC=C3)CC4=CC=C(C)C=C4)O2)OC

For research use only.

Storage

3 years,-20°C,powder
1 years,-80°C,in solvent

Shipping

Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)

Preparing Stock Solutions

1 mg5 mg10 mg
1 mM2.3840 mL11.9198 mL23.8396 mL
5 mM0.4768 mL2.3840 mL4.7679 mL
10 mM0.2384 mL1.1920 mL2.3840 mL
50 mM0.0477 mL0.2384 mL0.4768 mL

Description

COH000 is an allosteric, covalent and irreversible inhibitor with IC50 of 0.2 μM for SUMOylation in vitro.

Targets

E1 activating [1]
(Cell-free assay)
0.2 μM