[CAS NO. 193746-75-7] SB 242235
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PRODUCTS SPECIFICATIONS [193746-75-7]
Catalog
SLK-S0387
Brand
Selleck
CAS
193746-75-7
DESCRIPTION [193746-75-7]
Overview
| MDL | MFCD08690575 |
|---|---|
| Molecular Weight | 353.39 |
| Molecular Formula | C19H20FN5O |
| SMILES | COC1=NC=CC(C2=C(C3=CC=C(F)C=C3)N=CN2C4CCNCC4)=N1 |
For research use only.
Storage
3 years,-20°C,powder
1 years,-80°C,in solvent
1 years,-80°C,in solvent
Shipping
Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)
Preparing Stock Solutions
| 1 mg | 5 mg | 10 mg | |
| 1 mM | 2.8297 mL | 14.1487 mL | 28.2973 mL |
| 5 mM | 0.5659 mL | 2.8297 mL | 5.6595 mL |
| 10 mM | 0.2830 mL | 1.4149 mL | 2.8297 mL |
| 50 mM | 0.0566 mL | 0.2830 mL | 0.5659 mL |
Description
SB-242235 is a potent and selective inhibitor, inhibits p38 MAP kinase induced by IL-1β with an IC50 of approximately 1.0 μM in primary human chondrocytes.
Targets
| p38 MAPK [1] (in immune complex kinase assays) |
| 1.0 μM |
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