[CAS NO. 1093108-50-9] BI-671800
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PRODUCTS SPECIFICATIONS [1093108-50-9]
Catalog
SLK-S0495
Brand
Selleck
CAS
1093108-50-9
DESCRIPTION [1093108-50-9]
Overview
| MDL | - |
|---|---|
| Molecular Weight | 501.50 |
| Molecular Formula | C25H26F3N5O3 |
| SMILES | - |
For research use only.
Storage
3 years,-20°C,powder
1 years,-80°C,in solvent
1 years,-80°C,in solvent
Shipping
Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)
Preparing Stock Solutions
| 1 mg | 5 mg | 10 mg | |
| 1 mM | 1.9940 mL | 9.9701 mL | 19.9402 mL |
| 5 mM | 0.3988 mL | 1.9940 mL | 3.9880 mL |
| 10 mM | 0.1994 mL | 0.9970 mL | 1.9940 mL |
| 50 mM | 0.0399 mL | 0.1994 mL | 0.3988 mL |
Description
BI-671800 (AP-761, Cmpd A) is a highly specific and potent antagonist of with IC50 of 4.5 nM and 3.7 nM for PGD2 binding to human CRTH2 and murine CRTH2, respectively. BI-671800 is associated with a small improvement in FEV1 in symptomatic controller-naïve asthma patients, and in patients on ICS.
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