[CAS NO. 68528-80-3] DSS Crosslinker

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PRODUCTS SPECIFICATIONS [68528-80-3]

Catalog

SLK-S0657

Brand

Selleck

CAS

68528-80-3

DESCRIPTION [68528-80-3]

Overview

MDL	MFCD00049059
Molecular Weight	368.34
Molecular Formula	C16H20N2O8
SMILES	O(C(CCCCCCC(ON1C(=O)CCC1=O)=O)=O)N2C(=O)CCC2=O

For research use only.

Storage

3 years,-20°C,powder
1 years,-80°C,in solvent

Shipping

Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)

Preparing Stock Solutions

Concentration Volume Mass	1 mg	5 mg	10 mg
1 mM	2.7149 mL	13.5744 mL	27.1488 mL
5 mM	0.5430 mL	2.7149 mL	5.4298 mL
10 mM	0.2715 mL	1.3574 mL	2.7149 mL
50 mM	0.0543 mL	0.2715 mL	0.5430 mL

Description

DSS Crosslinker (Disuccinimidyl suberate) is a membrane permeable homobifunctional crosslinking agent and a non-cleavable ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).

References

[1] JeeYoung Kim, et al. Biomedicines. 2020 Dec 11;8(12):596.

Synonyms

Octanedioic acid, 1,8-bis(2,5-dioxo-1-pyrrolidinyl) ester

2,5-Pyrrolidinedione, 1,1′-[(1,8-dioxo-1,8-octanediyl)bis(oxy)]bis-

Disuccinimidyl suberate

Octanedioic acid di-N-hydroxysuccinimide ester

Suberic acid bis(N-hydroxy succinimide ester)

NSC 340008