[CAS NO. 479413-70-2] AUDA

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PRODUCTS SPECIFICATIONS [479413-70-2]

Catalog

SLK-S0752

Brand

Selleck

CAS

479413-70-2

DESCRIPTION [479413-70-2]

Overview

MDL	MFCD12912267
Molecular Weight	392.58
Molecular Formula	C23H40N2O3
SMILES	N(C(NCCCCCCCCCCCC(O)=O)=O)C12CC3CC(C1)CC(C2)C3

For research use only.

Storage

3 years,-20°C,powder
1 years,-80°C,in solvent

Shipping

Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)

Preparing Stock Solutions

Concentration Volume Mass	1 mg	5 mg	10 mg
1 mM	2.5473 mL	12.7363 mL	25.4725 mL
5 mM	0.5095 mL	2.5473 mL	5.0945 mL
10 mM	0.2547 mL	1.2736 mL	2.5473 mL
50 mM	0.0509 mL	0.2547 mL	0.5095 mL

Description

AUDA (compound 43) is a potent inhibitor of with IC50 of 18 nM and 69 nM for the mouse sEH and human sEH, respectively. AUDA has anti-inflammatory activity that reduces the protein expression of , , and . AUDA downregulates and signaling pathways.

Targets

References

[1] Christophe Morisseau, et al. Biochem Pharmacol. 2002 May 1;63(9):1599-608.
[2] Na Dai, et al. Exp Ther Med. 2019 May;17(5):3580-3588.q
[3] Xin-Wei Dong, et al. Toxicology. 2017 Aug 15;389:31-41.

Synonyms

Dodecanoic acid, 12-[[(tricyclo[3.3.1.1^3,7]dec-1-ylamino)carbonyl]amino]-

12-[[(Tricyclo[3.3.1.1^3,7]dec-1-ylamino)carbonyl]amino]dodecanoic acid

12-(3-Adamantan-1-yl-ureido)dodecanoic acid

A 003564556

AUDA

A003564556