[CAS NO. 135239-65-5]  RP-64477

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PRODUCTS SPECIFICATIONS [135239-65-5]

Catalog
SLK-S0820
Brand
Selleck
CAS
135239-65-5

DESCRIPTION [135239-65-5]

Overview

MDLMFCD00902351
Molecular Weight498.72
Molecular FormulaC29H42N2O3S
SMILESO=C(NCCCC)C1=CC=C(SC)C(NC(C2=CC=C(OCCCCCCCCCC)C=C2)=O)=C1

For research use only.

Storage

3 years,-20°C,powder
1 years,-80°C,in solvent

Shipping

Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)

Description

RP-64477 is a potent inhibitor of the cholesterol esterifying enzyme . RP-64477 inhibits ACAT activity with IC50 of 113 nM, 503 nM, and 180 nM in human intestinal (CaCo-2), hepatic (HepG2) and monocytic (THP-1) cell assays, respectively.

Targets

ACAT [1]
(CaCo-2 cell-based assay)
ACAT [1]
(THP-1 cell-based assay)
ACAT [1]
(HepG2 cell-based assay)
113 nM180 nM503 nM