[CAS NO. 3258-02-4] EIDD-1931

Ships within

Stock

Price

Qty

Total

$0.00

Please click "REQUEST A QUOTE" button if you need other sizes or custom synthesis

request a quote

If there is no stock, or you need other sizes or custom synthesis, please:

PRODUCTS SPECIFICATIONS [3258-02-4]

Catalog

SLK-S0833

Brand

Selleck

CAS

3258-02-4

DESCRIPTION [3258-02-4]

Overview

MDL	MFCD01675695
Molecular Weight	259.22
Molecular Formula	C9H13N3O6
SMILES	O[C@H]1[C@@](O[C@H](CO)[C@H]1O)(N2C(=O)NC(=NO)C=C2)[H]

For research use only.

Storage

3 years,-20°C,powder
1 years,-80°C,in solvent

Shipping

Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)

Preparing Stock Solutions

Concentration Volume Mass	1 mg	5 mg	10 mg
1 mM	3.8577 mL	19.2886 mL	38.5773 mL
5 mM	0.7715 mL	3.8577 mL	7.7155 mL
10 mM	0.3858 mL	1.9289 mL	3.8577 mL
50 mM	0.0772 mL	0.3858 mL	0.7715 mL

Description

EIDD-1931 (Beta-d-N4-hydroxycytidine, β-d-N4-hydroxycytidine, NHC) is an active metabolite of EIDD-2801, a promising inhibitor. EIDD-1931 (NHC) has broad spectrum antiviral activity against , , , and or with average IC50 of 0.15 μM, as well as increased potency against a coronavirus bearing resistance mutations to the nucleoside analog inhibitor remdesivir.

References

[1] Timothy P Sheahan, et al. Sci Transl Med. 2020 Apr 29;12(541):eabb5883.

Synonyms

Uridine, 4-oxime

Cytidine, N-hydroxy-

N⁴-Hydroxycytidine

N-Hydroxycytidine

EIDD 1931

NHC