[CAS NO. 1448440-52-5]  SP-13786

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PRODUCTS SPECIFICATIONS [1448440-52-5]

Catalog
SLK-S0842
Brand
Selleck
CAS
1448440-52-5

DESCRIPTION [1448440-52-5]

Overview

MDLMFCD29477499
Molecular Weight344.32
Molecular FormulaC17H14F2N4O2
SMILESC(NCC(=O)N1[C@H](C#N)CC(F)(F)C1)(=O)C=2C3=C(N=CC2)C=CC=C3

For research use only.

Storage

3 years,-20°C,powder
1 years,-80°C,in solvent

Shipping

Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)

Preparing Stock Solutions

1 mg5 mg10 mg
1 mM2.9043 mL14.5214 mL29.0428 mL
5 mM0.5809 mL2.9043 mL5.8086 mL
10 mM0.2904 mL1.4521 mL2.9043 mL
50 mM0.0581 mL0.2904 mL0.5809 mL

Description

SP-13786 (UAMC-1110)(compound 60) is a potent and selective inhibitor of and with IC50 of 3.2 nM and 1.8 μM, respectively.

Targets

FAP [1]
(Cell-free assay)
PREP [1]
(Cell-free assay)
3.2 nM1.8 μM


Synonyms

4-Quinolinecarboxamide, N-[2-[(2S)-2-cyano-4,4-difluoro-1-pyrrolidinyl]-2-oxoethyl]-
N-[2-[(2S)-2-Cyano-4,4-difluoro-1-pyrrolidinyl]-2-oxoethyl]-4-quinolinecarboxamide
(S)-N-(2-(2-Cyano-4,4-difluoropyrrolidin-1-yl)-2-oxoethyl)quinoline-4-carboxamide