[CAS NO. 17328-16-4] TC-E 5003
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PRODUCTS SPECIFICATIONS [17328-16-4]
Catalog
SLK-S0855
Brand
Selleck
CAS
17328-16-4
DESCRIPTION [17328-16-4]
Overview
| MDL | MFCD00028183 |
|---|---|
| Molecular Weight | 401.26 |
| Molecular Formula | C16H14Cl2N2O4S |
| SMILES | O=S(C1=CC=C(NC(CCl)=O)C=C1)(C2=CC=C(NC(CCl)=O)C=C2)=O |
For research use only.
Storage
3 years,-20°C,powder
1 years,-80°C,in solvent
1 years,-80°C,in solvent
Shipping
Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)
Preparing Stock Solutions
| 1 mg | 5 mg | 10 mg | |
| 1 mM | 2.4921 mL | 12.4607 mL | 24.9215 mL |
| 5 mM | 0.4984 mL | 2.4921 mL | 4.9843 mL |
| 10 mM | 0.2492 mL | 1.2461 mL | 2.4921 mL |
| 50 mM | 0.0498 mL | 0.2492 mL | 0.4984 mL |
Description
TC-E 5003 (NSC 30176, Compound 2e) is a selective inhibitor of with IC50 of 1.5 μM. TC-E 5003 modulates the lipopolysaccharide (LPS)-induced and signaling pathways and can possibly be further developed as an anti-inflammatory compound.
In vitro
TC-E 5300 regulates inflammatory responses by inhibiting the c-Jun expression and NF-κB signal transduction, which inhibits the expression of various inflammatory genes by downregulating these transcriptional factors.
References
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