[CAS NO. 107438-79-9] Ginkgolide J

Ships within

Stock

Price

Qty

Total

$0.00

Please click "REQUEST A QUOTE" button if you need other sizes or custom synthesis

request a quote

If there is no stock, or you need other sizes or custom synthesis, please:

PRODUCTS SPECIFICATIONS [107438-79-9]

Catalog

SLK-S0920

Brand

Selleck

CAS

107438-79-9

DESCRIPTION [107438-79-9]

Overview

MDL	-
Molecular Weight	424.40
Molecular Formula	C20H24O10
SMILES	O[C@@]12C34[C@]5(C6([C@](O3)(OC(=O)[C@@H]6O)[H])[C@H](C(C)(C)C)[C@@H](O)[C@]5(OC4=O)[H])C[C@@]1(OC(=O)[C@H]2C)[H]

For research use only.

Storage

3 years,-20°C,powder
1 years,-80°C,in solvent

Shipping

Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)

Preparing Stock Solutions

Concentration Volume Mass	1 mg	5 mg	10 mg
1 mM	2.3563 mL	11.7813 mL	23.5627 mL
5 mM	0.4713 mL	2.3563 mL	4.7125 mL
10 mM	0.2356 mL	1.1781 mL	2.3563 mL
50 mM	0.0471 mL	0.2356 mL	0.4713 mL

Description

Ginkgolide J is a minor constituent of terpene trilactone mixture of Ginkgo biloba leaves extract that inhibits with IC50 of 2.0 μM. Ginkgolide J also inhibits of rodent hippocampal neurons caused by Aβ1–42. Ginkgolide J exhibits activity.

Targets

GlyR ^[1]

2.0 μM

References

[1] Elena L Kondratskaya, et al. Neurochem Int . 2004 Feb;44(3):171-7.
[2] Yujie Zhao, et al. Mol Med Rep . 2021 Aug;24(2):555.
[3] Ottavio Vitolo, et al. Neurobiol Aging . 2009 Feb;30(2):257-65.

Synonyms

9H-1,7a-(Epoxymethano)-1H,6aH-cyclopenta[c]furo[2,3-b]furo[3′,2′:3,4]cyclopenta[1,2-d]furan-5,9,12(4H)-trione, 3-(1,1-dimethylethyl)hexahydro-2,4,7b-trihydroxy-8-methyl-, (1S,2R,3S,3aS,4R,6aR,7aR,7bR,8S,10aS,11aS)-

Ginkgolide A, 7-hydroxy-, (7β)-

(1S,2R,3S,3aS,4R,6aR,7aR,7bR,8S,10aS,11aS)-3-(1,1-Dimethylethyl)hexahydro-2,4,7b-trihydroxy-8-methyl-9H-1,7a-(epoxymethano)-1H,6aH-cyclopenta[c]furo[2,3-b]furo[3′,2′:3,4]cyclopenta[1,2-d]furan-5,9,12(4H)-trione

9H-1,7a-(Epoxymethano)-1H,6aH-cyclopenta[c]furo[2,3-b]furo[3′,2′:3,4]cyclopenta[1,2-d]furan-5,9,12(4H)-trione, 3-(1,1-dimethylethyl)hexahydro-2,4,7b-trihydroxy-8-methyl-, [1S-(1α,2α,3β,3aR*,4β,6aα,7aα,7bα,8α,10aα,11aR*)]-

Ginkgolide J

BN 52024