[CAS NO. 1191911-26-8]  CZC-25146

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PRODUCTS SPECIFICATIONS [1191911-26-8]

Catelog
SLK-S2002
Brand
Selleck
CAS
1191911-26-8

DESCRIPTION [1191911-26-8]

Overview

MDLMFCD28160475
Molecular Weight488.54
Molecular FormulaC22H25FN6O4S
SMILESCS(=O)(NC1=CC=CC=C1NC2=NC(NC3=CC=C(N4CCOCC4)C=C3OC)=NC=C2F)=O

For research use only.

Storage

3 years,-20°C,powder
1 years,-80°C,in solvent

Shipping

Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)

Preparing Stock Solutions

1 mg5 mg10 mg
1 mM2.0469 mL10.2346 mL20.4692 mL
5 mM0.4094 mL2.0469 mL4.0938 mL
10 mM0.2047 mL1.0235 mL2.0469 mL
50 mM0.0409 mL0.2047 mL0.4094 mL

Description

CZC-25146 is a potent and selective inhibitor with IC50 of 4.76 nM and 6.87 nM for human wild type LRRK2 and G2019S LRRK2, respectively.

Targets

human wild type LRRK2 [1]
(Cell-free assay)
G2019S LRRK2 [1]
(Cell-free assay)
4.76 nM6.87 nM