[CAS NO. 945526-43-2] ISCK03

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PRODUCTS SPECIFICATIONS [945526-43-2]

Catalog

SLK-S2070

Brand

Selleck

CAS

945526-43-2

DESCRIPTION [945526-43-2]

Overview

MDL	MFCD12031591
Molecular Weight	355.45
Molecular Formula	C19H21N3O2S
SMILES	O=S(C1=CC=C(C(C)(C)C)C=C1)(NC2=CC=C(N3C=CN=C3)C=C2)=O

For research use only.

Storage

3 years,-20°C,powder
1 years,-80°C,in solvent

Shipping

Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)

Preparing Stock Solutions

Concentration Volume Mass	1 mg	5 mg	10 mg
1 mM	2.8133 mL	14.0667 mL	28.1334 mL
5 mM	0.5627 mL	2.8133 mL	5.6267 mL
10 mM	0.2813 mL	1.4067 mL	2.8133 mL
50 mM	0.0563 mL	0.2813 mL	0.5627 mL

Description

ISCK03 (N-(4-imidazol-1-yl phenyl)sulfonamide) is a cell-permeable inhibitor of signaling.ISCK03 inhibits SCF-induced c-c-kit phosphorylation and downstream ERK phosphorylation.

Targets

SCF ^[1]

c-Kit ^[1]

References

[1] Na YJ, et al. Biochem Pharmacol. 2007 1;74(5):780-6.