[CAS NO. 529-44-2] Myricetin

Name: Myricetin
Brand: Arctom Scientific
SKU: SLK-S2326

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PRODUCTS SPECIFICATIONS [529-44-2]

Distributor

Catalog

SLK-S2326

Brand

Selleck

CAS

529-44-2

DESCRIPTION [529-44-2]

Overview

MDL	MFCD00006827
Molecular Weight	318.24
Molecular Formula	C15H10O8
SMILES	O=C1C=2C(OC(=C1O)C3=CC(O)=C(O)C(O)=C3)=CC(O)=CC2O

For research use only.

Storage

3 years,-20°C,powder
1 years,-80°C,in solvent

Shipping

Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)

Preparing Stock Solutions

Concentration Volume Mass	1 mg	5 mg	10 mg
1 mM	3.1423 mL	15.7114 mL	31.4228 mL
5 mM	0.6285 mL	3.1423 mL	6.2846 mL
10 mM	0.3142 mL	1.5711 mL	3.1423 mL
50 mM	0.0628 mL	0.3142 mL	0.6285 mL

Description

Myricetin, a natural flavonoid with antioxidant and anti tumor properties, is a novel inhibitor of activity and transformation of JB6 P+ mouse epidermal cells. It also inhibits with Kd of 0.17 μM.

Targets

MEK1 ^[4]	PI3Kγ ^[5]
	0.17 μM(Kd)

In vitro

Myricetin(Cannabiscetin) is a flavonoid found in many grapes, berries, fruits, vegetables, herbs, as well as other plants, which has antioxidant and anti tumor properties. Myricetin has antioxidant properties. In vitro research suggests that myricetin in high concentrations can modify LDL cholesterol such that uptake by white blood cells is increased. Studies shows that high myricetin consumption reduces the risk of prostate cancer and pancreatic cancer.

References

[1] Knekt P, et al. Am J Clin Nutr, 2002, 76(3), 560-568.
[2] Nothlings U, et al. Am J Epidemiol, 2007, 166(8), 924-931.
[3] Phillips PA, et al. Cancer Lett, 2011, 308(2), 181-188.
[4] Lee KW, et al. Carcinogenesis. 2007, 28(9):1918-27.
[5] Walker EH, et al. Mol Cell. 2000, 6(4):909-19.

Synonyms

4H-1-Benzopyran-4-one, 3,5,7-trihydroxy-2-(3,4,5-trihydroxyphenyl)-

Flavone, 3,3′,4′,5,5′,7-hexahydroxy-

3,5,7-Trihydroxy-2-(3,4,5-trihydroxyphenyl)-4H-1-benzopyran-4-one

Cannabiscetin

3,5,7,3′,4′,5′-Hexahydroxyflavone

Myricetin

Myricetol

3,3′,4′,5,5′,7-Hexahydroxyflavone

NSC 407290

LDN 0014058

NCBI 5281672

3,5,7-Trihydroxy-2-(3,4,5-trihydroxyphenyl)chromen-4-one

3,5,7-Trihydroxy-2-(3,4,5-trihydroxyphenyl)-4H-chromen-4-one