[CAS NO. 1069858-99-6] ML359

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PRODUCTS SPECIFICATIONS [1069858-99-6]

Catalog

SLK-S2846

Brand

Selleck

CAS

1069858-99-6

DESCRIPTION [1069858-99-6]

Overview

MDL	-
Molecular Weight	417.93
Molecular Formula	C23H28ClNO4
SMILES	-

For research use only.

Storage

3 years,-20°C,powder
1 years,-80°C,in solvent

Shipping

Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)

Preparing Stock Solutions

Concentration Volume Mass	1 mg	5 mg	10 mg
1 mM	2.3927 mL	11.9637 mL	23.9275 mL
5 mM	0.4785 mL	2.3927 mL	4.7855 mL
10 mM	0.2393 mL	1.1964 mL	2.3927 mL
50 mM	0.0479 mL	0.2393 mL	0.4785 mL

Description

ML359 is a small molecule inhibitor of .

Targets

PDI ^[1]

In vitro

ML359 shows no cytotoxicity in three human cell lines (HeLa, HEK293, and HepG2), and some activity in inhibiting platelet aggregation in vitro (25% inhibition at 30 µM).

References

[1] Carol Khodier, et al. In: Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010-2013 Apr 12.
[2] Bendapudi PK, et, al. Blood (2014) 124 (21): 2880.