[CAS NO. 2438-72-4] Bufexamac
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PRODUCTS SPECIFICATIONS [2438-72-4]
Store
Catalog
SLK-S3023
Brand
Selleck
CAS
2438-72-4
DESCRIPTION [2438-72-4]
Overview
| MDL | MFCD00078936 |
|---|---|
| Molecular Weight | 223.27 |
| Molecular Formula | C12H17NO3 |
| SMILES | C(C(NO)=O)C1=CC=C(OCCCC)C=C1 |
For research use only.
Storage
3 years,-20°C,powder
1 years,-80°C,in solvent
1 years,-80°C,in solvent
Shipping
Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)
Preparing Stock Solutions
| 1 mg | 5 mg | 10 mg | |
| 1 mM | 4.4789 mL | 22.3944 mL | 44.7888 mL |
| 5 mM | 0.8958 mL | 4.4789 mL | 8.9578 mL |
| 10 mM | 0.4479 mL | 2.2394 mL | 4.4789 mL |
| 50 mM | 0.0896 mL | 0.4479 mL | 0.8958 mL |
Description
Bufexamac(Bufexamic acid) is a inhibitor for release with of 8.9 μM.
Features
A specific inhibitor of class IIB histone deacetylases.
Targets
| IFN-α [1] |
| 8.9 μM |
In vitro
Bufexamac is a specific inhibitor of class IIB histone deacetylases (HDAC6 and HDAC10). Treatment of peripheral blood mononuclear cells with bufexamac inhibits the secretion of IFN-α. Bufexamac is a frequent and relevant contact sensitizer. Bufexamac is a non-steroidal anti-inflammatory drug.
References
Synonyms
Benzeneacetamide, 4-butoxy-N-hydroxy-
Acetohydroxamic acid, 2-(p-butoxyphenyl)-
4-Butoxy-N-hydroxybenzeneacetamide
CP 1044J3
p-Butoxyphenylacethydroxamic acid
4-Butoxyphenylacethydroxamic acid
p-Butoxyphenylacetohydroxamic acid
Droxaryl
Bufexamac
2-(p-Butoxyphenyl)acetohydroxamic acid
Bufexamic acid
Droxarol
Flogocid
Flogocid N plastigel
Parfenal
Parfenac
Anderm
Mofenar
Malipuran
Feximac
Norfemac
Trolab
2-(4-Butoxyphenyl)acetohydroxamic acid
2-(4-Butoxyphenyl)-N-hydroxyacetamide
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