[CAS NO. 26095-59-0] Otilonium Bromide

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PRODUCTS SPECIFICATIONS [26095-59-0]

Catalog

SLK-S3047

Brand

Selleck

CAS

26095-59-0

DESCRIPTION [26095-59-0]

Overview

MDL	MFCD00211142
Molecular Weight	563.57
Molecular Formula	C29H43BrN2O4
SMILES	O(CCCCCCCC)C1=C(C(NC2=CC=C(C(OCC[N+](CC)(CC)C)=O)C=C2)=O)C=CC=C1.[Br-]

For research use only.

Storage

3 years,-20°C,powder
1 years,-80°C,in solvent

Shipping

Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)

Preparing Stock Solutions

Concentration Volume Mass	1 mg	5 mg	10 mg
1 mM	1.7744 mL	8.8720 mL	17.7440 mL
5 mM	0.3549 mL	1.7744 mL	3.5488 mL
10 mM	0.1774 mL	0.8872 mL	1.7744 mL
50 mM	0.0355 mL	0.1774 mL	0.3549 mL

Description

Otilonium bromide is an antimuscarinic.

Targets

mAChR ^[1]

In vitro

Otilonium bromide is a quaternary ammonium compound whose spasmolytic action, selective on the distal gastrointestinal tract, is mainly due to its direct myolytic properties. This drug modifies Ca2+ fluxes from extracellular and intracellular pools in the intestinal smooth muscle and is poorly absorbed, thus it exerts its action locally, without any considerable systemic effect.

References

[1] Maggi CA, et al. Arch Int Pharmacodyn Ther, 1983, 264(2), 305-323.
[2] Battaglia G, et al. Aliment Pharmacol Ther, 1998, 12(10), 1003-1010.

Synonyms

Ethanaminium, N,N-diethyl-N-methyl-2-[[4-[[2-(octyloxy)benzoyl]amino]benzoyl]oxy]-, bromide (1:1)

Ammonium, diethyl(2-hydroxyethyl)methyl-, bromide, p-[o-(octyloxy)benzamido]benzoate

Ethanaminium, N,N-diethyl-N-methyl-2-[[4-[[2-(octyloxy)benzoyl]amino]benzoyl]oxy]-, bromide

Benzoic acid, p-[o-(octyloxy)benzamido]-, ester with diethyl(2-hydroxyethyl)methylammonium bromide

Otilonium bromide

Spasmomen

Octylonium bromide

SP 63