[CAS NO. 5534-09-8] Beclomethasone dipropionate

Name: Beclomethasone dipropionate
Brand: Arctom Scientific
SKU: SLK-S3078

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PRODUCTS SPECIFICATIONS [5534-09-8]

Distributor

Catalog

SLK-S3078

Brand

Selleck

CAS

5534-09-8

DESCRIPTION [5534-09-8]

Overview

MDL	-
Molecular Weight	521.04
Molecular Formula	C28H37ClO7
SMILES	C(COC(CC)=O)(=O)[C@]1(OC(CC)=O)[C@]2(C)[C@@](C[C@@H]1C)([C@]3([C@](Cl)([C@@H](O)C2)[C@]4(C)C(CC3)=CC(=O)C=C4)[H])[H]

For research use only.

Storage

3 years,-20°C,powder
1 years,-80°C,in solvent

Shipping

Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)

Preparing Stock Solutions

Concentration Volume Mass	1 mg	5 mg	10 mg
1 mM	1.9192 mL	9.5962 mL	19.1924 mL
5 mM	0.3838 mL	1.9192 mL	3.8385 mL
10 mM	0.1919 mL	0.9596 mL	1.9192 mL
50 mM	0.0384 mL	0.1919 mL	0.3838 mL

Description

Beclomethasone dipropionate(Beclovent,Beconase,Vancenase) is a potent glucocorticoid steroid used for the treatment of rhinitis and sinusitis.

Targets

Glucocorticoid receptor ^[1]

In vitro

Beclomethasone dipropionate (BDP) is an anti-inflammatory corticosteroid available for the treatment of asthma and allergic rhinitis (AR). BDP is previously developed as aqueous nasal formulations for the treatment of AR. BDP is also available in dry nasal aerosol formulations as chlorofluoro carbon (CFC) metered-dose inhaler nasal sprays, but CFC-containing formulations have been withdrawn from the market and currently are not available.BDP hydrofluoroalkane (HFA) inhalation aerosol currently is available for patient use and indicated for the maintenance treatment of asthma as prophylactic therapy in patients 5 years of age and older.BDP HFA nasal aerosol, an intranasal aerosol formulation, has been developed recently for the treatment of AR.

References

[1] Ratner PH, et al. Clin Ther, 2012, 34(6), 1422-1431.
[2] Busse WW, et al. J Allergy Clin Immunol, 1999, 104(6), 1215-1222.

Synonyms

Pregna-1,4-diene-3,20-dione, 9-chloro-11-hydroxy-16-methyl-17,21-bis(1-oxopropoxy)-, (11β,16β)-

Pregna-1,4-diene-3,20-dione, 9-chloro-11β,17,21-trihydroxy-16β-methyl-, 17,21-dipropionate

(11β,16β)-9-Chloro-11-hydroxy-16-methyl-17,21-bis(1-oxopropoxy)pregna-1,4-diene-3,20-dione

Beclometasone dipropionate

9α-Chloro-16β-methylprednisolone 17,21-dipropionate

Propaderm

Beclomethasone 17,21-dipropionate

Sanasthmyl

Becotide

Vanceril

Beclometasone 17,21-dipropionate

Propaderm Forte

Beclomethasone 17α,21-dipropionate

Beclomet

Beclovent

Vancenase

Beconase

Beclazone 50

Beclazone 250

Beclazone

Beclotide

Beclotide 100

Vanceril DS

Beconase AQ

Vancenase AQ

Aerobec

QVAR

Beclomethasone dipropionate

Beclate

Aldecin AQ nasal

Belchlorhinol

Anceron

Viarex

Beclacin

Andion

Sch 8020W

Sanasthmax

Sanasthymyl

Aldecin

Becodisks

Viarox

Inalone O

Inalone R

Entyderma

Clenil A

Belcoforte

Becloval

Korbutone

Rino-Clenil

Beclovent Inhaler

Belcomet

Ventolair

Qvar 50

orBec

Topster

Nasobec

Clenil

Becloneb