[CAS NO. 877387-37-6]  GSK5182

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PRODUCTS SPECIFICATIONS [877387-37-6]

Catalog
SLK-S3449
Brand
Selleck
CAS
877387-37-6

DESCRIPTION [877387-37-6]

Overview

MDL-
Molecular Weight417.54
Molecular FormulaC27H31NO3
SMILES-

For research use only.

Storage

3 years,-20°C,powder
1 years,-80°C,in solvent

Shipping

Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)

Preparing Stock Solutions

1 mg5 mg10 mg
1 mM2.3950 mL11.9749 mL23.9498 mL
5 mM0.4790 mL2.3950 mL4.7900 mL
10 mM0.2395 mL1.1975 mL2.3950 mL
50 mM0.0479 mL0.2395 mL0.4790 mL

Description

GSK5182, 4-hydroxytamoxifen analog, is a specific inverse agonist of that inhibits pro-inflammatory cytokine-induced catabolic factors.

Targets

ERRγ [1]

In vitro

GSK5182, a small-molecule ERRγ inverse agonist, inhibits pro-inflammatory cytokine-induced catabolic factors in mouse articular chondrocytes.