[CAS NO. 782500-75-8] Albiglutide Fragment

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PRODUCTS SPECIFICATIONS [782500-75-8]

Catalog

SLK-S3734

Brand

Selleck

CAS

782500-75-8

DESCRIPTION [782500-75-8]

Overview

MDL	-
Molecular Weight	3283.6
Molecular Formula	C148H224N40O45
SMILES	-

For research use only.

Storage

3 years,-20°C,powder
1 years,-80°C,in solvent

Shipping

Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)

Preparing Stock Solutions

Concentration Volume Mass	1 mg	5 mg	10 mg
1 mM	0.3045 mL	1.5227 mL	3.0454 mL
5 mM	0.0609 mL	0.3045 mL	0.6091 mL
10 mM	0.0305 mL	0.1523 mL	0.3045 mL
50 mM	-	-	-

Description

Albiglutide fragment is one copy of a 30-amino-acid sequence of modified human GLP-1 (fragment 7-36).

In vitro

Albiglutide is a recombinant fusion protein consisting of two copies of a 30-amino-acid sequence of modified human GLP-1 (fragment 7-36), modified with a glycine substituted for the naturally occurring alanine at position 8 in order to augment resistance to DPP-4.

References

[1] Rendell MS, et al. Expert Opin Biol Ther. 2016, 16(12):1557-1569.
[2] Weike Bao, et al. PLoS One. 2011, 6(8): e23570.