[CAS NO. 5053-08-7] Fenspiride HCl
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PRODUCTS SPECIFICATIONS [5053-08-7]
Distributor
Catalog
SLK-S4090
Brand
Selleck
CAS
5053-08-7
DESCRIPTION [5053-08-7]
Overview
| MDL | - |
|---|---|
| Molecular Weight | 296.79 |
| Molecular Formula | C15H20N2O2.HCl |
| SMILES | O=C1OC2(CCN(CCC3=CC=CC=C3)CC2)CN1.Cl |
For research use only.
Storage
3 years,-20°C,powder
1 years,-80°C,in solvent
1 years,-80°C,in solvent
Shipping
Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)
Preparing Stock Solutions
| 1 mg | 5 mg | 10 mg | |
| 1 mM | 3.3694 mL | 16.8469 mL | 33.6939 mL |
| 5 mM | 0.6739 mL | 3.3694 mL | 6.7388 mL |
| 10 mM | 0.3369 mL | 1.6847 mL | 3.3694 mL |
| 50 mM | 0.0674 mL | 0.3369 mL | 0.6739 mL |
Description
Fenspiride(Decaspiride) is a bronchodilator with anti-inflammatory properties, inhibiting phosphodiesterase 4 and phosphodiesterase 3 activities with logIC50 values of 4.16 and 3.44, respectively, in human isolated bronchi.
Features
Produces less than 25% inhibition of phosphodiesterase 1 and phosphodiesterase 2 activities.
In vitro
Fenspiride induces potentiation of the effects of isoprenaline and sodium nitroprusside with logEC50 of 4.1 and 3.5, respectively, in human isolated bronchi.
References
Synonyms
1-Oxa-3,8-diazaspiro[4.5]decan-2-one, 8-(2-phenylethyl)-, hydrochloride (1:1)
1-Oxa-3,8-diazaspiro[4.5]decan-2-one, 8-phenethyl-, monohydrochloride
1-Oxa-3,8-diazaspiro[4.5]decan-2-one, 8-(2-phenylethyl)-, monohydrochloride
Fenspiride hydrochloride
JP 428
8-Phenethyl-1-oxa-3,8-diazaspiro[4.5]decan-2-one hydrochloride
Decaspiride
Fluiden
Viarespan
NAT 333
Decaspir
Tegencia
NDR 5998A
Pneumorel
Erespal
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