[CAS NO. 17692-31-8] Dropropizine

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PRODUCTS SPECIFICATIONS [17692-31-8]

Catalog

SLK-S4138

Brand

Selleck

CAS

17692-31-8

DESCRIPTION [17692-31-8]

Overview

MDL	MFCD00079124
Molecular Weight	236.31
Molecular Formula	C13H20N2O2
SMILES	C(C(CO)O)N1CCN(CC1)C2=CC=CC=C2

For research use only.

Storage

3 years,-20°C,powder
1 years,-80°C,in solvent

Shipping

Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)

Preparing Stock Solutions

Concentration Volume Mass	1 mg	5 mg	10 mg
1 mM	4.2317 mL	21.1586 mL	42.3173 mL
5 mM	0.8463 mL	4.2317 mL	8.4635 mL
10 mM	0.4232 mL	2.1159 mL	4.2317 mL
50 mM	0.0846 mL	0.4232 mL	0.8463 mL

Description

Dropropizine (UCB-1967,(±)- Dropropizine) is a racemic non-opiate antitussive agent, it is used as a cough suppressant.

In vitro

Dropropizine shows neither mutagenic nor clastogenic effects in Chinese hamster V79 and human EUE cells, while Lithium carbonicum manifestes a weak and mazindol a medium genotoxic response which is in both cases reduce in the presence of microsomal fraction S9.

References

[1] Slamenov?D, et al. Mutat Res, 1986, 169(3), 171-177
[2] Sutovska M, et al. Bratisl Lek Listy, 2009, 110(5), 269-275.
[3] Nosalova G, et al. Acta Vet. Brno, 2007, 76, 27-33.
[4] Nos醠
[5] Franova S, et al. Advances in Phytomedicine, 2006, 2, 111–131.

Synonyms

1,2-Propanediol, 3-(4-phenyl-1-piperazinyl)-

3-(4-Phenyl-1-piperazinyl)-1,2-propanediol

Dropropizine

Dopropizin

Larylin

Catabex

Katril

Ribex

Tussilex

U.C.B. 1967

Ditustat

(±)-Dropropizine