[CAS NO. 125079-83-6] CU-CPT-8m
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PRODUCTS SPECIFICATIONS [125079-83-6]
Store
Catalog
SLK-S4461
Brand
Selleck
CAS
125079-83-6
DESCRIPTION [125079-83-6]
Overview
| MDL | MFCD31692371 |
|---|---|
| Molecular Weight | 252.27 |
| Molecular Formula | C14H12N4O |
| SMILES | O=C(C1=C2N=CC=C(C3=CC=CC(C)=C3)N2N=C1)N |
For research use only.
Storage
3 years,-20°C,powder
1 years,-80°C,in solvent
1 years,-80°C,in solvent
Shipping
Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)
Preparing Stock Solutions
| 1 mg | 5 mg | 10 mg | |
| 1 mM | 3.9640 mL | 19.8200 mL | 39.6401 mL |
| 5 mM | 0.7928 mL | 3.9640 mL | 7.9280 mL |
| 10 mM | 0.3964 mL | 1.9820 mL | 3.9640 mL |
| 50 mM | - | - | - |
Description
CU-CPT-8m (CPD1578) is a specific antagonist of with IC50 of 67 nM and Kd of 220 nM.
In vitro
CU-CPT8m, recognizes a pocket on the interface of two copies of TLR8 and prevents them from undergoing conformational changes that are necessary for the proinflammatory signaling.
References
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