[CAS NO. 83-07-8] 4-Aminoantipyrine

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PRODUCTS SPECIFICATIONS [83-07-8]

Catalog

SLK-S4509

Brand

Selleck

CAS

83-07-8

DESCRIPTION [83-07-8]

Overview

MDL	MFCD00003145
Molecular Weight	203.24
Molecular Formula	C11H13N3O
SMILES	O=C1N(N(C)C(C)=C1N)C2=CC=CC=C2

For research use only.

Storage

3 years,-20°C,powder
1 years,-80°C,in solvent

Shipping

Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)

Preparing Stock Solutions

Concentration Volume Mass	1 mg	5 mg	10 mg
1 mM	4.9203 mL	24.6015 mL	49.2029 mL
5 mM	0.9841 mL	4.9203 mL	9.8406 mL
10 mM	0.4920 mL	2.4601 mL	4.9203 mL
50 mM	0.0984 mL	0.4920 mL	0.9841 mL

Description

4-Aminoantipyrine(Ampyrone) is a metabolite of aminopyrine with analgesic, anti-inflammatory, and antipyretic properties. It is used as a reagent for biochemical reactions producing peroxides or phenols.

In vitro

The level of glutathione(GSH) in single erythrocytes is impacted slightly at low AAP(4-aminoantipyrine) concentrations probably due to the protection of glutathione reductase. When AAP concentration further increases, AAP has a significant influence on GSH.

In vivo

4-aminoantipyrine (4-AA) is not genotoxic and mutagenic in vivo, it can interfere with DNA damaging agents biological activities and may reduce the effectiveness of DNA damage-based chemotherapy.

References

[1] Vinagre AM, et al. Braz J Med Biol Res. 2016, 49(3).
[2] Teng Y, et al. J Hazard Mater. 2011, 192(3):1766-1771.
[3] Berno CR, et al. Mutat Res Genet Toxicol Environ Mutagen. 2016, 805:19-24.

Synonyms

3H-Pyrazol-3-one, 4-amino-1,2-dihydro-1,5-dimethyl-2-phenyl-

Antipyrine, 4-amino-

4-Amino-1,2-dihydro-1,5-dimethyl-2-phenyl-3H-pyrazol-3-one

4-AAP

4-Aminoantipyrine

4-Amino-1,5-dimethyl-2-phenyl-3-pyrazolone

4-Aminophenazone

Ampyrone

1-Phenyl-2,3-dimethyl-4-amino-5-pyrazolone

Aminoantipyrine

4-Amino-2,3-dimethyl-1-phenyl-3-pyrazolin-5-one

Aminoazophene

4-Amino-1,5-dimethyl-2-phenylpyrazolin-3-one

4-Amino-2,3-dimethyl-1-phenyl-5-pyrazolone

4-Amino-2,3-dimethyl-1-phenylpyrazolin-5-one

4-Amino-1,5-dimethyl-2-phenyl-4-pyrazolin-3-one

4-Amino-1,5-dimethyl-3-oxo-2-phenylpyrazoline

Metapirazone

Solvapyrin A

4-Amino-1-phenyl-2,3-dimethyl-5-pyrazolone

1,2-Dihydro-1,5-dimethyl-2-phenyl-4-amino-3H-pyrazol-3-one

4-Amino-1,5-dimethyl-2-phenyl-1,2-dihydro-3H-pyrazol-3-one

NSC 60242

4-Amino-1,5-dimethyl-2-phenyl-1,2-dihydropyrazol-3-one

(2,3-Dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)amine

4-Amino-1,5-dimethyl-2-phenyl-1H-pyrazol-3(2H)-one

4-Amino-1,2-dihydro-2,3-dimethyl-1-phenylpyrazol-5-one

4-Amino-1,5-dimethyl-2-phenyl-1H-pyrazol-3-one

4-Amino-1,5-dimethyl-2-phenyl-1,2-dihydro-3H-pyrazole-3-one