[CAS NO. 20426-12-4] 4-Hydroxychalcone

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PRODUCTS SPECIFICATIONS [20426-12-4]

Catalog

SLK-S4763

Brand

Selleck

CAS

20426-12-4

DESCRIPTION [20426-12-4]

Overview

MDL	MFCD00016488
Molecular Weight	224.25
Molecular Formula	C15H12O2
SMILES	C(C=CC1=CC=C(O)C=C1)(=O)C2=CC=CC=C2

For research use only.

Storage

3 years,-20°C,powder
1 years,-80°C,in solvent

Shipping

Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)

Preparing Stock Solutions

Concentration Volume Mass	1 mg	5 mg	10 mg
1 mM	4.4593 mL	22.2965 mL	44.5931 mL
5 mM	0.8919 mL	4.4593 mL	8.9186 mL
10 mM	0.4459 mL	2.2297 mL	4.4593 mL
50 mM	0.0892 mL	0.4459 mL	0.8919 mL

Description

4-Hydroxychalcone (P-Cinnamoylphenol) is a chalcone metabolite with diverse biological activities. It inhibits TNFα-induced NF-κB pathway activation in a dose-dependent manner and also activates BMP signaling.

Targets

NF-κB ^[1]

In vivo

4-Hydroxychalcone attenuates hyperaldosteronism, inflammation, and renal injury in cryptochrome-null mice.

References

[1] Qu Q, et al. Biomed Res Int. 2014, 2014:603415.

Synonyms

2-Propen-1-one, 3-(4-hydroxyphenyl)-1-phenyl-

Chalcone, 4-hydroxy-

3-(4-Hydroxyphenyl)-1-phenyl-2-propen-1-one

4-Hydroxychalcone

4-Hydroxystyryl phenyl ketone

(4-Hydroxybenzylidene)acetophenone

(4-Hydroxybenzal)acetophenone

1-Phenyl-3-(4-hydroxyphenyl)-2-propen-1-one

NSC 60593

p-Hydroxychalcone