[CAS NO. 89796-99-6] Aceclofenac

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PRODUCTS SPECIFICATIONS [89796-99-6]

Catalog

SLK-S4835

Brand

Selleck

CAS

89796-99-6

DESCRIPTION [89796-99-6]

Overview

MDL	MFCD00864296
Molecular Weight	354.18
Molecular Formula	C16H13Cl2NO4
SMILES	N(C1=C(CC(OCC(O)=O)=O)C=CC=C1)C2=C(Cl)C=CC=C2Cl

For research use only.

Storage

3 years,-20°C,powder
1 years,-80°C,in solvent

Shipping

Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)

Preparing Stock Solutions

Concentration Volume Mass	1 mg	5 mg	10 mg
1 mM	2.8234 mL	14.1171 mL	28.2342 mL
5 mM	0.5647 mL	2.8234 mL	5.6468 mL
10 mM	0.2823 mL	1.4117 mL	2.8234 mL
50 mM	0.0565 mL	0.2823 mL	0.5647 mL

Description

Aceclofenac (Preservex, Airtal) is a non-steroidal anti-inflammatory drug (NSAID) with anti-inflammatory and analgesic properties.

In vivo

Long term oral administration of aceclofenac causes gastrointestinal (GI) ulcers and GI bleeding. Aceclofenac is well absorbed orally with hepatic first pass metabolism. It exhibits elimination half life of 4h, volume of distribution 25 L, 99 % of protein binding and 60-70% of bioavailability after oral administration.

References

[1] Faiyaz Shakeel, et al. J Bioequiv Availab. 2009, 1:013-017.

Synonyms

Benzeneacetic acid, 2-[(2,6-dichlorophenyl)amino]-, carboxymethyl ester

Aceclofenac

Falcol

Gerbin

2-[[2-[(2,6-Dichlorophenyl)amino]phenyl]acetoxy]acetic acid

Airtal

Tresquim

Biofenac

PR 82/3

Aceclofar

Bristaflam

Glycolic acid 2-[o-(2,6-dichloroanilino)phenyl]acetate

Zerodol

Hifenac

Preservex

[2-[(2,6-Dichlorophenyl)amino]phenyl]acetoxyacetic acid

Hifenac-TL

Dolokind

Acepac

Flexidol

Aceclofenac BP

Aceclo

Aceclo Plus

[2-(2,6-Dichloro-phenylamino)-phenyl]-acetic acid carboxymethyl ester

2-[2-[2-(2,6-Dichloroanilino)phenyl]acetyl]oxyacetic acid