[CAS NO. 1650550-25-6] Enasidenib Mesylate
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PRODUCTS SPECIFICATIONS [1650550-25-6]
Catalog
SLK-S4929
Brand
Selleck
CAS
1650550-25-6
DESCRIPTION [1650550-25-6]
Overview
| MDL | - |
|---|---|
| Molecular Weight | 569.48 |
| Molecular Formula | C20H21F6N7O4S |
| SMILES | - |
For research use only.
Storage
3 years,-20°C,powder
1 years,-80°C,in solvent
1 years,-80°C,in solvent
Shipping
Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)
Preparing Stock Solutions
| 1 mg | 5 mg | 10 mg | |
| 1 mM | 1.7560 mL | 8.7799 mL | 17.5599 mL |
| 5 mM | 0.3512 mL | 1.7560 mL | 3.5120 mL |
| 10 mM | 0.1756 mL | 0.8780 mL | 1.7560 mL |
| 50 mM | 0.0351 mL | 0.1756 mL | 0.3512 mL |
Description
Enasidenib (Idhifa, AG-221) mesylate is an orally available, selective and potent inhibitor of .
Targets
| IDH2 [1] |
In vitro
The compound has been demonstrated to reduce 2-HG levels by >90% and reverse histone and deoxyribonucleic acid (DNA) hypermethylation in vitro, and to induce differentiation in leukemia cell models.
References
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