[CAS NO. 90-50-6] 3,4,5-Trimethoxycinnamic acid
Please click "REQUEST A QUOTE" button if you need other sizes or custom synthesis
request a quote
If there is no stock, or you need other sizes or custom synthesis, please:
PRODUCTS SPECIFICATIONS [90-50-6]
Distributor
Catalog
SLK-S4961
Brand
Selleck
CAS
90-50-6
DESCRIPTION [90-50-6]
Overview
| MDL | MFCD00004388 |
|---|---|
| Molecular Weight | 238.24 |
| Molecular Formula | C12H14O5 |
| SMILES | O(C)C1=C(OC)C(OC)=CC(C=CC(O)=O)=C1 |
For research use only.
Storage
3 years,-20°C,powder
1 years,-80°C,in solvent
1 years,-80°C,in solvent
Shipping
Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)
Preparing Stock Solutions
| 1 mg | 5 mg | 10 mg | |
| 1 mM | 4.1974 mL | 20.9872 mL | 41.9745 mL |
| 5 mM | 0.8395 mL | 4.1974 mL | 8.3949 mL |
| 10 mM | 0.4197 mL | 2.0987 mL | 4.1974 mL |
| 50 mM | 0.0839 mL | 0.4197 mL | 0.8395 mL |
Description
3,4,5-Trimethoxycinnamic acid (TMCA) is one of the constituents of Polygalae Radix and may exert anti-seizure activity by acting at the GABAA/BZ receptor complex.
Targets
| GABA receptor [1] |
In vivo
TMCA decreased the locomotor activity in mice, prolonged total sleep time, and reduced sleep latency induced by pentobarbital. TMCA also increased the total sleep time and non-rapid eye movement (NREM) sleep. It alters sleep architecture through GABAAergic systyems. TMCA exhibits anti-stress actions by the suppression of norepinephrine (NE) content in locus coeruleus (LC) induced by corticotrophin-releasing hormone (CRH).
References
Synonyms
2-Propenoic acid, 3-(3,4,5-trimethoxyphenyl)-
Cinnamic acid, 3,4,5-trimethoxy-
3-(3,4,5-Trimethoxyphenyl)-2-propenoic acid
3,4,5-Trimethoxycinnamic acid
O-Methylsinapic acid
3,4,5-Trimethoxyphenylacrylic acid
3-(3,4,5-Trimethoxyphenyl)propenoic acid
NSC 66175
3-(3,4,5-Trimethoxyphenyl)acrylic acid
Powered by Arctom Copyright © 2026 Arctom. All rights
reserved.