[CAS NO. 134-47-4] AMI-1 (free acid)

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PRODUCTS SPECIFICATIONS [134-47-4]

Catalog

SLK-S5445

Brand

Selleck

CAS

134-47-4

DESCRIPTION [134-47-4]

Overview

MDL	MFCD00035715
Molecular Weight	504.49
Molecular Formula	C21H16N2O9S2
SMILES	OC=1C2=C(C=C(S(=O)(=O)O)C1)C=C(NC(NC3=CC4=C(C=C3)C(O)=CC(S(=O)(=O)O)=C4)=O)C=C2

For research use only.

Storage

3 years,-20°C,powder
1 years,-80°C,in solvent

Shipping

Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)

Preparing Stock Solutions

Concentration Volume Mass	1 mg	5 mg	10 mg
1 mM	1.9822 mL	9.9110 mL	19.8220 mL
5 mM	0.3964 mL	1.9822 mL	3.9644 mL
10 mM	0.1982 mL	0.9911 mL	1.9822 mL
50 mM	-	-	-

Description

AMI-1 is a potent and specific inhibitor with IC50 of 3.0 μM and 8.8 μM for yeast Hmt1p and human PRMT1, respectively.

Targets

HMT ^[1]	human PRMT1 ^[1]	yeast Hmt1p ^[1] (Cell-free assay)
		3.0 μM

References

[1] Donghang Cheng, et al. J Biol Chem . 2004 Jun 4;279(23):23892-9.

Synonyms

2-Naphthalenesulfonic acid, 7,7′-(carbonyldiimino)bis[4-hydroxy-

2-Naphthalenesulfonic acid, 7,7′-ureylenebis[4-hydroxy-

1-Naphthol-3-sulfonic acid, 6,6′-ureylenebis-

7,7′-(Carbonyldiimino)bis[4-hydroxy-2-naphthalenesulfonic acid]

I Acid Urea

J acid urea

N,N′-Bis[1-oxy-3-sulfonaphthyl(6)]urea

N,N′-Bis[1-hydroxy-3-sulfonaphthyl(6)]urea

N,N′-Bis(7-sulfo-5-hydroxy-2-naphthyl)urea

N,N′-Bis(5-hydroxy-7-sulfo-2-naphthyl)urea

6,6′-Ureylenebis(1-naphthol-3-sulfonic acid)

Urea J Acid

7,7′-Ureylenebis(4-hydroxy-2-naphthalenesulfonic acid)

Scarlet Acid

5,5′-Dihydroxy-2,2′-dinaphthylcarbamide-7,7′-disulfonic acid

Carbonyl J

NSC 1699

NSC 45174