[CAS NO. 3420-72-2] Flavokawain A

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PRODUCTS SPECIFICATIONS [3420-72-2]

Catalog

SLK-S5600

Brand

Selleck

CAS

3420-72-2

DESCRIPTION [3420-72-2]

Overview

MDL	MFCD00017174
Molecular Weight	314.33
Molecular Formula	C18H18O5
SMILES	O(C)C1=C(C(C=CC2=CC=C(OC)C=C2)=O)C(O)=CC(OC)=C1

For research use only.

Storage

3 years,-20°C,powder
1 years,-80°C,in solvent

Shipping

Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)

Description

Flavokawain A, extracted from kava, is an apoptotic inducers and anticarcinogenic agent. Flavokawain A can down-regulation of antiapoptotic proteins, such as , thereby changing the balance between apoptotic and antiapoptotic molecules and then induce cell death in tumor cells.

Targets

Bcl-xL ^[1]

Survivin ^[1]

XIAP ^[1]

References

[1] Xiaolin Zi, Anne R Simoneau. Cancer Res. 2005 Apr 15;65(8):3479-86.

Synonyms

2-Propen-1-one, 1-(2-hydroxy-4,6-dimethoxyphenyl)-3-(4-methoxyphenyl)-

Chalcone, 2′-hydroxy-4,4′,6′-trimethoxy-

1-(2-Hydroxy-4,6-dimethoxyphenyl)-3-(4-methoxyphenyl)-2-propen-1-one

2′-Hydroxy-4,4′,6′-trimethoxychalcone

NSC 37445