[CAS NO. 65836-72-8] DKM 2-93
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PRODUCTS SPECIFICATIONS [65836-72-8]
Catalog
SLK-S5841
Brand
Selleck
CAS
65836-72-8
DESCRIPTION [65836-72-8]
Overview
| MDL | MFCD01733639 |
|---|---|
| Molecular Weight | 243.69 |
| Molecular Formula | C11H14ClNO3 |
| SMILES | O=C(NCC1=CC=C(OC)C(OC)=C1)CCl |
For research use only.
Storage
3 years,-20°C,powder
1 years,-80°C,in solvent
1 years,-80°C,in solvent
Shipping
Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)
Description
DKM 2-93 is a relatively selective lead inhibitor of .
Targets
| UBA5 [1] |
In vitro
DKM 2-93 not only impairs pancreatic cancer cell survival in PaCa2, but also Panc1 cells with 50 % effective concentration values of 90 and 30 μM, respectively.
In vivo
DKM 2-93 daily treatment significantly impairs tumor growth of PaCa2 cells in vivo in tumor xenograft studies in immune-deficient mice without causing any weight loss or overt toxicity.
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