[CAS NO. 162359-55-9] Fingolimod

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PRODUCTS SPECIFICATIONS [162359-55-9]

Catalog

SLK-S5950

Brand

Selleck

CAS

162359-55-9

DESCRIPTION [162359-55-9]

Overview

MDL	MFCD14705150
Molecular Weight	307.47
Molecular Formula	C19H33NO2
SMILES	C(CC(CO)(CO)N)C1=CC=C(CCCCCCCC)C=C1

For research use only.

Storage

3 years,-20°C,powder
1 years,-80°C,in solvent

Shipping

Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)

Description

Fingolimod (FTY-720A, FTY-720) is a modulator used for the treatment of relapsing-remitting multiple sclerosis.

Targets

S1P receptor ^[1]

In vitro

The main immunomodulatory mechanism of action of fingolimod is based on its effect on lymphocyte homing. It reversibly redistributes T and B cells from the circulation to secondary lymphoid organs like peripheral and mesenteric lymph nodes and Peyer's patches, thereby causing a state of peripheral lymphopenia.

References

[1] Huwiler A, et al. Pharmacol Ther. 2018, 185:34-49.
[2] Hu Y, et al. Mol Cell Neurosci. 2011, 48(1):72-81.
[3] Xue Y, et al. Cell Death Dis. 2022 Jul 12;13(7):602.

Synonyms

1,3-Propanediol, 2-amino-2-[2-(4-octylphenyl)ethyl]-

2-Amino-2-[2-(4-octylphenyl)ethyl]-1,3-propanediol

Fingolimod

2-Amino-2-[2-(4-octylphenyl)ethyl]-1,3-propandiol

2-Amino-2-[2-(4-octylphenyl)ethyl]propane-1,3-diol