[CAS NO. 1207660-00-1]  Indophagolin

Ships within Stock Price Qty Total
$0.00
$0.00
Please click "REQUEST A QUOTE" button if you need other sizes or custom synthesis
request a quote
If there is no stock, or you need other sizes or custom synthesis, please:

PRODUCTS SPECIFICATIONS [1207660-00-1]

Catalog
SLK-S6087
Brand
Selleck
CAS
1207660-00-1

DESCRIPTION [1207660-00-1]

Overview

MDLMFCD14721653
Molecular Weight523.75
Molecular FormulaC19H15BrClF3N2O3S
SMILESO=S(C1=CC2=C(C=C1Br)CCN2C(C3CC3)=O)(NC4=CC=C(Cl)C(C(F)(F)F)=C4)=O

For research use only.

Storage

3 years,-20°C,powder
1 years,-80°C,in solvent

Shipping

Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)

Preparing Stock Solutions

1 mg5 mg10 mg
1 mM1.9093 mL9.5465 mL19.0931 mL
5 mM0.3819 mL1.9093 mL3.8186 mL
10 mM0.1909 mL0.9547 mL1.9093 mL
50 mM0.0382 mL0.1909 mL0.3819 mL

Description

Indophagolin, a potent indoline-containing autophagy inhibitor with IC50 of 140 nM, antagonizes the purinergic receptor  as well as  and  with IC50s of 2.71, 2.40 and 3.49 μM, respectively, also has a strong antagonistic effect on serotonin receptor  with IC50 of 1.0 μM.

Targets

5-HT6 [1]
(in cell-based assays)
P2X1 [1]
(in calcium influx assays)
P2X4 [1]
(in calcium influx assays)
P2X3 [1]
(in calcium influx assays)
1.0 μM2.40 μM2.71 μM3.49 μM