[CAS NO. 35920-39-9] 5'-N-Ethylcarboxamidoadenosine (NECA)

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PRODUCTS SPECIFICATIONS [35920-39-9]

Catalog

SLK-S6347

Brand

Selleck

CAS

35920-39-9

DESCRIPTION [35920-39-9]

Overview

MDL	MFCD00069195
Molecular Weight	308.29
Molecular Formula	C12H16N6O4
SMILES	O[C@H]1[C@](N2C=3C(N=C2)=C(N)N=CN3)(O[C@H](C(NCC)=O)[C@H]1O)[H]

For research use only.

Storage

3 years,-20°C,powder
1 years,-80°C,in solvent

Shipping

Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)

Preparing Stock Solutions

Concentration Volume Mass	1 mg	5 mg	10 mg
1 mM	3.2437 mL	16.2185 mL	32.4370 mL
5 mM	0.6487 mL	3.2437 mL	6.4874 mL
10 mM	0.3244 mL	1.6218 mL	3.2437 mL
50 mM	0.0649 mL	0.3244 mL	0.6487 mL

Description

5'-N-Ethylcarboxamidoadenosine (NECA, 5'-(N-Ethylcarboxamido)adenosine, Adenosine-5'N-ethylcarboxamide, 5'-Ethylcarboxamidoadenosine) is a stable, nonselective agonist. 5'-N-Ethylcarboxamidoadenosine acts via multiple mechanisms including: reducing diabetes-induced oxidative stress, inhibiting gene expression of , and , and blocking activation of the pathway.

Targets

References

[1] Nehal M Elsherbiny, et al. Eur Cytokine Netw. Jul-Sep 2012;23(3):78-86.

Synonyms

β-D-Ribofuranuronamide, 1-(6-amino-9H-purin-9-yl)-1-deoxy-N-ethyl-

1-(6-Amino-9H-purin-9-yl)-1-deoxy-N-ethyl-β-D-ribofuranuronamide

744-96

Adenosine 5′-ethylcarboxamide

5′-N-Ethylcarboxamidoadenosine

Adenosine 5′-N-ethylcarboxamide

NECA

5′-N⁶-Ethylcarboxamidoadenosine

D-NECA