[CAS NO. 1191911-27-9] CZC-54252

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PRODUCTS SPECIFICATIONS [1191911-27-9]

Catalog

SLK-S6534

Brand

Selleck

CAS

1191911-27-9

MDL	MFCD26401527
Molecular Weight	504.99
Molecular Formula	C22H25ClN6O4S
SMILES	O(C)C=1C=C(C=CC1NC=2N=C(NC3=C(NS(C)(=O)=O)C=CC=C3)C(Cl)=CN2)N4CCOCC4

For research use only.

3 years,-20°C,powder
1 years,-80°C,in solvent

Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)

CZC-54252 is a potent and selective inhibitor with IC50s of 1.28 nM and 1.85 nM for human wild type LRRK2 and G2019S LRRK2, respectively.

LRRK2 (WT) ^[1] (Cell-free assay)	LRRK2 (G2019S) ^[1] (Cell-free assay)
1.28 nM	1.85 nM

Methanesulfonamide, N-[2-[[5-chloro-2-[[2-methoxy-4-(4-morpholinyl)phenyl]amino]-4-pyrimidinyl]amino]phenyl]-

N-[2-[[5-Chloro-2-[[2-methoxy-4-(4-morpholinyl)phenyl]amino]-4-pyrimidinyl]amino]phenyl]methanesulfonamide

CZC 54252