[CAS NO. 2259-96-3] Cyclothiazide

Name: Cyclothiazide
Brand: Arctom Scientific
SKU: SLK-S6611

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PRODUCTS SPECIFICATIONS [2259-96-3]

Distributor

Catalog

SLK-S6611

Brand

Selleck

CAS

2259-96-3

DESCRIPTION [2259-96-3]

Overview

MDL	MFCD00210192
Molecular Weight	389.88
Molecular Formula	C14H16ClN3O4S2
SMILES	O=S1(=O)NC(C2C3CC(C2)C=C3)NC=4C1=CC(S(N)(=O)=O)=C(Cl)C4

For research use only.

Storage

3 years,-20°C,powder
1 years,-80°C,in solvent

Shipping

Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)

Description

Cyclothiazide is a positive allosteric modulator of with critical roles in neurological development and function.

Targets

AMPA-type receptors ^[1]

In vitro

Cyclothiazide is known to produce a fast inhibition of AMPA receptor desensitization and a much slower potentiation of the AMPA current.

References

[1] Sergio Fucile, et al. Proc Natl Acad Sci U S A. 2006, 103(8): 2943–2947.

Synonyms

2H-1,2,4-Benzothiadiazine-7-sulfonamide, 3-bicyclo[2.2.1]hept-5-en-2-yl-6-chloro-3,4-dihydro-, 1,1-dioxide

2H-1,2,4-Benzothiadiazine-7-sulfonamide, 6-chloro-3,4-dihydro-3-(5-norbornen-2-yl)-, 1,1-dioxide

MDi 193

Anhydron

6-Chloro-3,4-dihydro-3-(5-norbornen-2-yl)-2H-1,2,4-benzothiadiazine-7-sulfonamide-1,1-dioxide

6-Chloro-3,4-dihydro-3-(5-norbornen-2-yl)-7-sulfamyl-1,2,4-benzothiadiazine-1,1-dioxide

6-Chloro-3-(5-norbornen-2-yl)-7-sulfamoyl-3,4-dihydro-2H-1,2,4-benzothiadiazine-1,1-dioxide

Cyclothiazide

Doburil

6-Chloro-3-(5-bicyclo[2.2.1]hept-2-enyl)-7-sulfamoyl-3,4-dihydro-1,2,4-benzothiadiazine 1,1-dioxide

Aquirel

Renazide

Valmiran

Fluidil

Lilly 35483