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Catalog:
SLK-S6651
Brand:
Selleck
CAS:
1161002-05-6
Overview
MDL
-
Molecular Weight
370.24
Molecular Formula
C19H16BrNO2
SMILES
-
For research use only.
Storage
3 years,-20°C,powder 1 years,-80°C,in solvent
Shipping
Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)
Preparing Stock Solutions
1 mg
5 mg
10 mg
1 mM
2.7010 mL
13.5048 mL
27.0095 mL
5 mM
0.5402 mL
2.7010 mL
5.4019 mL
10 mM
0.2701 mL
1.3505 mL
2.7010 mL
50 mM
0.0540 mL
0.2701 mL
0.5402 mL
Description
G15 is a cell-permeable high affinity and selective antagonist with an affinity of approximately 20 nM that displays no affinity for ERα and ERβ at concentrations up to 10 μM.
G15 inhibits GPER-mediated proliferation stimulated by 17β-estradiol (E2) in A549 and H1793 cell lines. G15 inhibits the response of GPER stimulated by E2 and G1 in A549 and H1793 cell lines.