[CAS NO. 630124-46-8] AST-487 (NVP-AST487)
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PRODUCTS SPECIFICATIONS [630124-46-8]
Store
Catalog
SLK-S6662
Brand
Selleck
CAS
630124-46-8
DESCRIPTION [630124-46-8]
Overview
| MDL | MFCD11983171 |
|---|---|
| Molecular Weight | 529.56 |
| Molecular Formula | C26H30F3N7O2 |
| SMILES | O=C(NC1=CC=C(OC2=NC=NC(NC)=C2)C=C1)NC3=CC=C(CN4CCN(CC)CC4)C(C(F)(F)F)=C3 |
For research use only.
Storage
3 years,-20°C,powder
1 years,-80°C,in solvent
1 years,-80°C,in solvent
Shipping
Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)
Preparing Stock Solutions
| 1 mg | 5 mg | 10 mg | |
| 1 mM | 1.8884 mL | 9.4418 mL | 18.8836 mL |
| 5 mM | 0.3777 mL | 1.8884 mL | 3.7767 mL |
| 10 mM | 0.1888 mL | 0.9442 mL | 1.8884 mL |
| 50 mM | 0.0378 mL | 0.1888 mL | 0.3777 mL |
Description
AST-487 (NVP-AST487), a N,N'-diphenyl urea,is an ATP competitive inhibitor of with ki of 0.12 μM.Besides FLT3, AST487 also inhibits with IC50 values below 1 μM.
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